2020 - Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability

nanomedicine 2020

Authors: Amanda Costa Caritá, Bruno Fonseca-Santos, Jemima Daniela Shultz, Bozena Michniak-Kohn, Marlus Chorilli, Gislaine Ricci Leonardi.

Abstract 

Vitamin C (Vit C) is a potent antioxidant with several applications in the cosmetic and pharmaceutical fields. However, the biggest challenge in the utilization of Vit C is to maintain its stability and improve its delivery to the active site. Several strategies have been developed such as: controlling the oxygen levels during formulation and storage, low pH, reduction of water content in the formulation and the addition of preservative agents. Additionally, the utilization of derivatives of Vit C and the development of micro and nanoencapsulated delivery systems have been highlighted. In this article, the multiple applications and mechanisms of action of vitamin C will be reviewed and discussed, as well as the new possibilities of delivery and improvement of stability.

DOI: https://doi.org/10.1016/j.nano.2019.102117

 

Artigos Relacionados - Artigos Científicos

07 Jun 2021 02:00

Authors: Rodrigo Yokota, Fernanda Aparecida Ronchi, Fernanda Barrinha Fernandes, Zaira Palomino Jara, [ ... ]

Artigos Cientificos em Destaque
27 Dec 2021 04:00

Authors: Alexandre B Cavalcanti, Fernando G Zampieri, Regis G Rosa, Luciano C P Azevedo, Viviane [ ... ]

Artigos Cientificos em Destaque
06 Jun 2021 05:00

Authors: Jemima Daniela Dias Moraes, Silvana Raquel Alina Bertolino, Silvia Lucia Cuffini, Diego Fernando [ ... ]

Artigos Cientificos em Destaque

© 2013 - 2024 Universidade Federal de São Paulo - Unifesp

Rua Botucatu, 740, 5º andar, sala 562, Edifício Octávio de Carvalho - Vila Clementino • CEP 04023-062 - São Paulo - SP 

+55 11 3385-4343 Ramal 3027 / +55 11 5576-4228 • ppg.medicinatranslacional@unifesp.br