Alianzas

Proyectos de investigación

- Terapias Celulares

Proyectos de investigación

-Cultura de queratinocitos cultivados en diferentes sustitutos dérmicos

 -Estudio sobre la Asociación de Factor de crecimiento epidérmico y N-acetilcisteína en cultivos

 -Modulación de la expresión por TGF 8361538; -Fibroblastos humanos cultivados genéticamente modificados

 -Proliferación de Pseudomonas aeruginosa luminiscentes

 -Cultivo de queratinocitos humanos y kgf en modelo experimental de quemadura

 -Pseudomonas aeruginosa y kgf: Evaluación de la proliferación bacteriana en un modelo experimental de quemadura

 -TGB B1 en la producción de colágeno en fibroblastos

 -TGF Beta1 en la producción de matriz celular extra en fibroblastos cultivados obtenidos a partir de queloide y piel normal sometida a hipoxia

Publicaciones

1. CAMPANER, A. B. ; FERREIRA, L. M. ; GRAGNANI, A. ; BRUDER, J. M. ; CUSIK, J. ; MORGAN, J. . Upregulation of TGF-beta1 Expression May Be Necessary but Is Not Sufficient for Excessive Scarring. J Invest Dermatol. 2006; 126:1168-76.

2. CAMPANER, A. B. ; FERREIRA, L. M. ; GRAGNANI, A. ; BRUDER, J. M. ; CUSIK, J. ; MORGAN, J. . Upregulation of TGF-[beta]1 Expression may be Necessary but is not Sufficient for Excessive Scarring. Plast Reconstr Surg, 2005;116(3).

3. GRAGNANI, A; SOBRAL, C. S. ; Morgan, J.R. ; Ferreira, L.M. . Inhibition of proliferation of Pseudomonas aeruginosa by KGF in an experimental burn model using human cultured keratinocytes. Burns (Oxford)http://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 33, p. 613-620, 2007.

4. GRAGNANI, A; SOBRAL, C. ; Morgan, J.R. ; CAO, X. ; Ferreira, L.M. . Human Keratinocytes Cultured on Collagen Matrix Used as an Experimental Burn Model. JOURNAL OF BURNS AND WOUNDS, v. 7, p. 53-59, 2007.

5. CAMPANER, A. ; GRAGNANI, A ; Morgan, J.R. ; Ferreira, L.M. . Modelo animal de quelóide utilizando fibroblastos modificados geneticamente. Revista da Sociedade Brasileira de Cirurgia Plástica, v. 22, p. 137-142, 2007.

6. CAMPANER, A. ; Ferreira, L.M. ; GRAGNANI, A ; BRUDER, J. M. ; CUSICK, J. ; Morgan, J.R. . Upregulation of TGF-beta1 Expression May Be Necessary but Is Not Sufficient. Journal of Investigative Dermatologyhttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 126, p. 1168-1176, 2006.

7. GRAGNANI, A; Morgan, J.R. ; Ferreira, L.M. . Experimental model of cultured skin graft. Acta Cirúrgica Brasileirahttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, São Paulo, v. 19, n.suplemento, p. 4-10, 2004.

8. GRAGNANI, A; Ferreira, L.M. ; Morgan, J.R. . Experimental Model of Cultured Keratinocytes. Acta Cirúrgica Brasileira (Impresso)http://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, São Paulo, v. 18, n.n. especia, p. 04-14, 2003.

9. GRAGNANI, A; Morgan, J.R. ; Ferreira, L.M. . Differentiation and barrier formation of a cultured composite skin graft. J Burn Care Rehabil, v. 23, n.2, p. 126-131, 2002.

10. GRAGNANI, A; Morgan, J.R. ; Ferreira, L.M. . Contraction of the composite skin graft and autograft. The Canadian Journal of Plastic Surgery, v. 10, n.4, p. 155-157, 2002.

Proyectos de investigación

-Etiología de la curación hipertrófica;

-Modelo de quemadura experimental;

-Modelo porcino (DUROC) de curación hipertrófica.

Publicaciones

1. Mitsunaga Junior, Jorge Kiyoshi ; Gragnani, Alfredo ; Ramos, Maria Luiza Christóvão ; Ferreira, Lydia Masako . Rat an experimental model for burns: A systematic review. Acta Cirúrgica Brasileira (Online), v. 27, p. 417-423, 2012.

Proyectos de investigación

-Etiología de la curación hipertrófica;

-Modelo de quemadura experimental;

-Modelo porcino (DUROC) de curación hipertrófica.

Proyectos de investigación

• Células dendríticas en aloinjerto de tejidos compuestos;
• Células dendríticas tolerogénicas e inducción de tolerancia específica del donante de antígenos para los aloinjertos de piel vascularizada;
• Inducción de la tolerancia a los trasplantes de compuestos alogénicos mediante el uso de radiación tópica FK506 y UVB asociada con el trasplante de médula ósea de precursores de Langerhans Celulas.

Publicaciones

1. HORIBE EK, SACKS J, UNADKAT J, RAIMONDI G, WANG Z, IKEGUCHI R, MARSTELLER D, FERREIRA LM, THOMSON AW, LEE WP, Feili-Hariri M. Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion. Transpl Immunol. 2008 Feb;18(4):307-18.

2. HORIBE EK, SACKS JM, AKSU AE, UNADKAT J, SONG DY, FERREIRA LM, FEILI-HARIRI M, LEE WP. Strauch's technique for epigastric free flaps in rats revisited: a simple and effective method to increase patency rates. J Reconstr Microsurg. 2007 Aug;23(6):321-8.

3. WEINSTOCK, M; COST, M ; ZHAN, W ; JINDAL, R ; SUCHER, R ; ROHAN, L ; FERREIRA, LM ; VENKATAMARANAN, R ; LEE, WP ; SCHNEEBERGER, S ; BRANDACHER, G ; GORANTLA, V . 45A: TARGETED SITE SPECIFIC IMMUNOSUPPRESSION WITH TOPICAL RAPAMYCIN AND MYCOPHENOLIC ACID IN COMPOSITE TISSUE ALLOTRANSPLANTATION. Plastic and Reconstructive Surgery (1963)http://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 125, p. 36, 2010.

4. WEINSTOCK, M.; WANG, Y. ; JINDAL, R. ; SUCHER, R. ; SOLARI, M. ; ZHANG, W. ; ZHANG, D. ; FERREIRA, L.M. ; GORANTLA, V. ; BRANDACHER, G. ; LEE, W.P.A. ; ZHENG, X.X. . LP30: TAILORING THE SEQUENCE AND DURATION OF CONVENTIONAL IMMUNOSUPPRESSIVE DRUGS TO INDUCE CTA TOLERANCE. Plastic and Reconstructive Surgery (1963)http://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 126, p. 724, 2010.

Proyectos de investigación

- Desenvolvimento de tecidos dentários e mineralizados construídos por Engenharia Tecidual a partir de germes de dentes humanos

Publicaciones

1. DUAILIBI S. E., DUAILIBI M. T., ZHANG W., ARISCAN R., VACANTI J. P., YELICK P. C. Bioengineered dental tissues grown in the rat jaw. 2008. J Dental research, 87:745-50;

2. DUAILIBI S. E., DUAILIBI M. T., VACANTI J. P., YELICK P. C. Prospects for tooth regeneration. 2006. Periodontology, 41:177-87;

3. DUAILIBI S. E., DUAILIBI M. T., ARISCAN R., VACANTI J. P. YELICK P. C. A mandibular model for tooth tissue engineering using post-natal dental steam cells. 2005. Periodontology;

4. DUAILIBI, M. T.; DUAILIBI, S. E.; YOUNG, C.; BARTLETT, J. D.; VACANTI, J. P.; YELICK, P. C. Bioengineered teeth from cultured rat tooth bud cells. Journal of Dental Research, Estados Unidos, v. 83, n. 7, p. 523-528, 2004.

5. PISCIOLARO, R. L. ; DUAILIBI, Monica Talarico ; NOVO, N. F. ; JULIANO, Y. ; Pallos D ; YELICK, P. C. ; VACANTI, J. P. ; FERREIRA, Lydia Masako ; DUAILIBI, S. E. . Tooth Tissue Engineering: The importance of blood products as a supplement in tissue culture medium for human Pulp Dental Stem Cells. TISSUE ENGINEERING. PART Ahttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 2639, p. VOL.21-2015, 2015

6. DUAILIBI SE; DUAILIBI, Monica Talarico ; FERREIRA, Lydia Masako ; Salmazi, K.I.C. ; Salvadori, MC ; Teixeira FS ; Pasquarelli A ; VACANTI, J. P. ; YELICK, Pamela Crotty . Tooth Tissue Engineering: The influence of hydrophilic surface on nano-crystalline diamonds films for human Dental Stem Cells. Tissue Engineering. Part Ahttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 00, p. 130718041709009-00, 2013.

7. DUAILIBI, Monica Talarico ; KULIKOWSKI, Leslie Domenici ; DUAILIBI SE ; LIPAY, Monica Vanucci ; MELARAGNO, Maria Isabel ; FERREIRA, Lydia Masako ; VACANTI, Joseph Phillip ; YELICK, Pamela Crotty . Cytogenetic instability of dental pulp stem cell lines. Journal of Molecular Histology (Print)http://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 43, p. 89-94, 2012.

8. DUAILIBI, Monica Talarico ; Duailibi, Silvio Eduardo ; DUAILIBI NETO, E.F. ; Negreiros, RM ; Jorge, WA ; FERREIRA, Lydia Masako ; VACANTI, Joseph Phillip ; YELICK, Pamela Crotty . Tooth Tissue Engineering: Optimal Dental Stem Cell Harvest Based on Tooth Development. Artificial Organshttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 35, p. E129-E135, 2011.

Patentes

UALIBI S. E., DUAILIBI M. T., YELICK P. C., VACANTI J. P. Uso de células-tronco, método de engenharia tecidual, sos de tecidos dentais e substituto biológico do dente. 2004.

Proyectos de investigación

- Fração vascular estromal e células tronco derivadas de tecido adiposo como enriquecedores de enxerto de gordura criopreservado

Publicaciones

1. ZANATA, FABIANA; BOWLES, ANNIE ; FRAZIER, TRIVIA ; CURLEY, J. LOWRY ; BUNNELL, BRUCE A. ; WU, XIYING ; WADE, JAMES ; DEVIREDDY, RAM ; GIMBLE, JEFFREY M. ; FERREIRA, LYDIA MASAKO . Effect of Cryopreservation on Human Adipose Tissue and Isolated Stromal Vascular Fraction Cells. PLASTIC AND RECONSTRUCTIVE SURGERYhttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 141, p. 232e-243e, 2018. 

2. THOMAS-PORCH, CAASY ; LI, JIE ; ZANATA, FABIANA ; MARTIN, ELIZABETH C. ; PASHOS, NICHOLAS ; GENEMARAS, KAYLYNN ; POCHE, J. NICHOLAS ; TOTARO, NICHOLAS P. ; BRATTON, MELYSSA R. ; GAUPP, DINA ; FRAZIER, TRIVIA ; WU, XIYING ; FERREIRA, LYDIA MASAKO ; TIAN, WEIDONG ; WANG, GUANGDI ; BUNNELL, BRUCE A. ; FLYNN, LAUREN ; HAYES, DANIEL ; GIMBLE, JEFFREY M. . Comparative Proteomic Analyses of Human Adipose Extracellular Matrices Decellularized Using Alternative Procedures. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART Ahttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 1, p. 1, 2018.

3. GIMBLE, JEFFREY M. ; RAY, STEPHEN P. ; ZANATA, FABIANA ; WU, XIYING ; WADE, JAMES ; KHOOBEHI, KAMRAN ; FERREIRA, LYDIA MASAKO ; BUNNELL, BRUCE A. . Adipose Derived Cells and Tissues for Regenerative Medicine. ACS Biomaterials Science & Engineeringhttp://buscatextual.cnpq.br/buscatextual/images/curriculo/jcr.gif, v. 1, p. e101, 2016.